THE FABULOUS HISTORY OF THE SOLVATED ELECTRON

The fabulous history of the solvated electron

The history of sciences is rich in founding experiments, which have given rise to such developments that they constituted full-fledged disciplines.Much wac 4011 more rarely, knowledge coming from very distant horizons converged at a moment to offer a very new vision of old results and to provoke an explosion of new research.This was the case for th

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Production of a Monoclonal Antibody to the Nucleocapsid Protein of SARS-CoV-2 and Its Application to ELISA-Based Detection Methods with Broad Specificity by Combined Use of Detector Antibodies

The coronavirus disease 2019 pandemic, elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is ongoing.Currently accessible antigen-detecting rapid diagnostic tests are limited by their low sensitivity and detection efficacy due to evolution of SARS-CoV-2 variants.Here, we produced and characterized an anti-SARS-CoV-2 nucleocap

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Combination of farnesyl-transferase inhibition with KRAS G12D targeting breaks down therapeutic resistance in pancreatic cancer

Pancreatic adenocarcinoma is one of the deadliest forms of cancer with no effective therapeutic options.A KRAS mutation can be found in up to 90% of all pancreatic tumors, making it a promising therapeutic target.The introduction of new KRAS inhibitors has been a milestone in the history of KRAS mutant tumors; however, therapeutic resistance limits

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